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10 人阅读发布时间:2026-01-26 13:48
The filtration of complex biotech drug formulations, such as high-concentration mAbs and encapsulated products, comes with unique challenges. These can include premature blocking due to high particulate loads, high differential pressures due to high viscosities, and risk of bacterial penetration. These challenges result in a need for larger filters or additional filters, leading to increased hold-up volume and higher product loss. Supor™ Prime sterilizing grade filters have been developed to meet these challenges. The high throughput of Supor Prime filters allows for reduced filtration area. By reducing the filter area, a smaller filter can be used resulting in increased product recovery per batch. Supor Prime filters are best suited for sterile filtration in the most critical process steps: post ultrafiltration/diafiltration (UF/DF), bulk fill of drug substance, and final fill of drug product.